2-[(Substituted-piperazinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2

Details 2-[(Substituted-piperazinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2 2-[(Substituted-piperazinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2

1974-11-13

1976-02-24

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424250, C07D40106

Patent

active

039403971

ABSTRACT:
Compounds of the following formula and their acid addition salts ##SPC1##
Wherein R.sup.1 and R.sup.2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, amino and trifluoromethyl; A is a straight or branched chain alkylene of 1 to 8 carbons; and Z is ##SPC2##
Wherein R.sup.3 is selected from phenyl, phenyl-lower alkyl, and substituted phenyl and phenyl-lower alkyl are disclosed. These compounds exhibit antidepressant activity. In addition these compounds are useful as antiinflammatory agents.

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