Substituted imidazoles having anti-cancer and cytokine inhibitor

Details Substituted imidazoles having anti-cancer and cytokine inhibitor Substituted imidazoles having anti-cancer and cytokine inhibitor

1996-09-23

1998-02-10

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514318, C07D21106, A61K 31445

Patent

active

057171009

ABSTRACT:
Compounds represented by formula I: ##STR1## are disclosed. AR represents an aromatic group containing 6-10 atoms; and ##STR2## represents a 4 to 6 membered non-aromatic heterocycle containing only one N atom.
A pharmaceutical composition is also included.
Methods of treating cancer and cytokine mediated diseases are also included.

REFERENCES:
patent: 3707475 (1972-12-01), Lombardino et al.
patent: 3772441 (1973-11-01), Lombardino et al.
patent: 3929807 (1975-12-01), Fitzi
patent: 3940486 (1976-02-01), Fitzi

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