Pyridine derivatives, their production and use

Details Pyridine derivatives, their production and use Pyridine derivatives, their production and use

1996-08-09

1998-02-10

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514346, 514352, 514357, 514344, 5462837, 546286, 546287, 546289, 546315, 546318, 546326, 546330, 546297, 546300, C07D21363, C07D21379, C07D21384, C07D21389

Patent

active

057169713

ABSTRACT:
Pyridine derivatives of the formula ##STR1## wherein the ring A stands for an optionally further substituted benzene ring; the ring B stands for an optionally substituted pyridine ring; Q stands for hydroxyl group, or OQ.sup.1 or Q.sup.1 wherein Q.sup.1 stands for an optionally substituted aliphatic hydrocarbon group; and n denotes 0 or 1, or their salts, which have potassium.channel opening activity and are useful as therapeutic agents of circulatory diseases such as angina pectoris, hypertension, etc.

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"The Merck Index", Eleventh Edition, Merck & Co., U.S.A. *Progabide, entry 7782 (1989).
Cameron et al., Chemical Abstracts, vol. 97, No. 25, 1982, Columbus, Ohio USA Abstract No. 215955df.
Hodogaya Chemical Co., Chemical Abstracts, vol. 97, No. 24, 1982, Columbus, Ohio USA Abstract No. 199542j.
Duennenberger et al., Chemical Abstracts, vol. 55, No. 20, 2 Oct., 1961, Columbus, Ohio Abstract No. 19747i.
Sidgwick, The Organic Chemistry Of Nitrogen, p. 382 Clarendon Press Oxford 1966.

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