Iodine compound for use as a tracer in radioimmunology

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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2601125R, 2602395, 424179, 424238, A61K 4300, G01N 3356, G01N 3360, C07C10352

Patent

active

043316468

ABSTRACT:
The compound is constituted by a conjugate compound of an antigen having a free carboxylic function and a dipeptide. The dipeptide is constituted by a product of condensation between tyrosine and a peptide, the tyrosine group of the dipeptide being labeled with radioactive iodine.
The compound is highly soluble in water and permits of good recognition by the antibody in antigen-antibody reactions.

REFERENCES:
patent: 4197286 (1980-04-01), Rao
patent: 4202874 (1980-05-01), Akerkar et al.
patent: 4207308 (1980-06-01), Spenny
patent: 4209614 (1980-06-01), Bernstein et al.
Radioimmunoassay of Biologically Active Compounds, Parker, Prentice-Hall, Inc., N.J., 1976, pp. 93-94.
Ohki et al., Prostaglandins, vol. 6, No. 2, Apr. 1974, pp. 137-148.

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