Substituted 4-phenoxy or 4-phenylthio prolines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514222, 544 12, 544 13, 544244, 544284, 544287, 544288, 544289, A61K 31505, A61K 3154, C07D40312, C07D41712

Patent

active

046818863

ABSTRACT:
This invention is directed to substituted 4-phenoxy and 4-phenylthio prolines of the formula ##STR1## which possess useful hypotensive activity.

REFERENCES:
patent: 3040042 (1962-06-01), Yale et al.
patent: 4105776 (1978-08-01), Ondetti et al.
patent: 4168267 (1979-09-01), Petrillo
patent: 4217347 (1980-08-01), Horovitz et al.
patent: 4316906 (1982-02-01), Ondetti et al.
patent: 4337201 (1982-06-01), Petrillo
patent: 4374829 (1983-02-01), Harris
patent: 4431644 (1984-02-01), Smith et al.
patent: 4431645 (1984-02-01), Smith et al.
Tanabe, Abstracts of Japanese Application 5151-555, published Nov. 1980.

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