Method for preparing tissue heart valve

Bleaching and dyeing; fluid treatment and chemical modification – Treatment of hides – skins – feathers and animal tissues – Internal tissues

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3 14, 3 15, D01C 300, A61F 122

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043504922

ABSTRACT:
A method for preparing an aortic heart valve for implantation wherein the area of the septal shelf of the right coronary cusp extending into the valve orifice is substantially reduced. The excised value is prepared for fixation by pressurizing the valve to close the valve cusps, and thereafter inverting the aortic vestibule tissue over a valve stent or other cylindrical form circumscribing the valve. As the vestibule tissue is inverted, the septal shelf muscle is pulled toward the outside wall of the valve. When the septal shelf has been displaced to the maximum extent possible while maintaining coaption of the valve leaflets, the valve is fixed with a tanning solution. The resulting valve, after being trimmed and mounted for implantation, has improved flow characteristics.

REFERENCES:
patent: 3570014 (1971-03-01), Hancock
patent: 3755823 (1973-09-01), Hancock
patent: 3966401 (1976-06-01), Hancock et al.
patent: 4050893 (1977-09-01), Hancock et al.
R. Gorlin and S. G. Gorlin, "Hydraulic Formula For Calculation of the Area of the Stenotic Mitral Valve, Other Cardiac Valves, And Central Circulatory Shunts. I.", Am. Heart Journal, 41, 1 (1951).
Michael V. Cohen and Richard Gorlin, "Modified Orifice Equation for the Calculation of Mitral Valve Area, " Am. Heart Journal, 84, 839 (1972).

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