Spiro-azabicyclic muscarinic agonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

540543, 546 18, 546 19, 514278, A61K 31395, C07D49720

Patent

active

049924362

ABSTRACT:
The present invention provides a spiro-azabicyclic compound or a salt or prodrug thereof, said compound comprising a saturated or unsaturated 5-membered heterocyclic ring containing two heteroatoms selected from oxygen, nitrogen and sulphur, no more than one of said heteroatoms being nitrogen; said heterocyclic ring having a spiro attachment to an optionally substituted azabicyclo[2.2.1]heptane or azabicyclo[3.2.1]octane ring system; which compounds are useful for the treatment of neurological and mental disorders.

REFERENCES:
patent: 4104397 (1978-08-01), Cohen et al.
patent: 4855290 (1989-08-01), Fisher et al.

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