Organic compounds -- part of the class 532-570 series – Organic compounds – Pteroyl per se or having -c- – wherein x is chalcogen – bonded...
Patent
1995-03-13
2000-06-13
Berch, Mark L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Pteroyl per se or having -c-, wherein x is chalcogen, bonded...
544265, 544266, 544271, 544276, 544277, 544280, 544311, 544312, 544316, 544317, 548255, 5482644, 5482654, 5482677, 5483241, 5483265, 548327, 5483275, 5483285, 5483311, 5483325, 5483381, C07D47318, C07D47334, C07D47316, C07D23954
Patent
active
060751436
ABSTRACT:
There are described N-ethylglycine derivatives of the formula I ##STR1## in which PG is a urethane-type or trityl-type amino protective group which is labile to weak acids, X is NH, O or S, Y is CH.sub.2, NH or O, and B' are bases customary in nucleotide chemistry, the exocyclic amino or hydroxyl groups of which being protected by suitable, known protective groups, or are base substitute compounds, and their salts with tert-organic bases, as well as a process for their preparation. The N-ethylglycine derivatives of the formula I are used in the preparation of PNA and PNA/DNA hybrids.
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Webb, JACS 108:2764
Breipohl Gerhard
Knolle Jochen
Uhlmann Eugen
Berch Mark L.
Hoechst Aktiengesellschaft
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