Surgery – Respiratory method or device – Ozone or ion generation
Patent
1977-08-29
1979-12-25
Michell, Robert W.
Surgery
Respiratory method or device
Ozone or ion generation
424 19, A61M 3100
Patent
active
041800737
ABSTRACT:
A self-powered device for delivering drug is disclosed. The device comprises (1) a substantially rigid housing, (2) a collapsible container storing a drug and having a passageway for delivering the drug in the housing, and (3) an expandable laminate positioned between the housing and the container. The laminate comprises (a) a lamina formed of an absorbent material laminated to (b) a lamina placed adjacent to the container and formed of a swellable hydrophilic polymer. In operation, when the device is in a biological environment, fluid from the environment is imbibed by the laminate into the housing causing the laminate to expand and exert pressure on the container, thereby collapsing the container and concomitantly pumping drug through the passageway from the device at a correspondingly controlled rate over a prolonged period of time.
REFERENCES:
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patent: 2858830 (1958-11-01), Robins
patent: 3732865 (1973-05-01), Higuchi et al.
patent: 3760805 (1973-09-01), Higuchi
patent: 3760984 (1973-09-01), Theeuwes
patent: 3971376 (1976-07-01), Wichterle
patent: 3987790 (1976-10-01), Eckenhoff et al.
patent: 3995631 (1976-12-01), Higuchi et al.
ALZA Corporation
Ciotti Thomas E.
Mandell Edward L.
Michell Robert W.
Rosenbaum C. F.
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