Cyclic amides

Details Cyclic amides Cyclic amides

Filed on

1996-08-27

Date issued

1997-12-16

Examiner

Rotman, Alan L.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Having -c-, wherein x is chalcogen, bonded directly to...

Other Related Categories

548512, C07D20934, A61K 3140

Type

Patent

Status

active

Patent number

056985797

Description

ABSTRACT:
Cyclic amides are inhibitors of tumor necrosis factor and can be used to combat cachexia, endotoxic shock, and retrovirus replication. A typical embodiment is 3-phenyl-3-(1-oxoisoindolin-2-yl)propionamide.

REFERENCES:
Chemical Abstracts #117:251172, 1992, by Padwa.
Chemical Abstracts #116:152338, 1992, Ocain.
Chemical Abstracts #115:256655, 1991, Ocain.
Chemical Abstracts #106:119777, Nefkens, 1985.

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