Aldose reductase inhibition by spiro indoline derivatives

Details Aldose reductase inhibition by spiro indoline derivatives Aldose reductase inhibition by spiro indoline derivatives

1984-03-19

1986-04-08

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548101, 548309, 548485, A61K 31415, C07D48710

Patent

active

045813663

ABSTRACT:
The invention concerns 1'-(4-bromo-2-fluorobenzyl)-7'-chloro-spiro[imidazolidine-4,3'-indoline]-2 ,2',5-trione in racemic or dextrorotatory form; pharmaceutical compositions thereof for use in the treatment or prophylaxis of certain complications of diabetes; and processes for its manufacture.

REFERENCES:
patent: 4490381 (1984-12-01), Brittain et al.

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