Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1998-09-10
2000-06-13
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424422, 424423, 424426, 424 7804, 514725, 514955, 6048901, 6048921, A61K 214, A61K 3107
Patent
active
060746610
ABSTRACT:
An implantable device is provided which incorporates a retinoid for improving the biocompatability of the device in eye tissue. The device may be bioerodible for the purpose of systemically or locally releasing a therapeutic agent in tissue or it may be a permanent implant which includes a surface treated with a retinoid for increasing the biocompatibility thereof.
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Giordano et al "Sustained Delivery of Retinoic Acid from Microspheres . . . " Inv Opth & Vis Sc Aug. 1993 vo. 34 No. 9.
Kivalo et al., Biodegradable Tube Implants in Experimental Glaucoma Surgery in the Rabbit, Journal of Materials Science: Materials in Medicine, 10(1) pp. 53-58, 1999.
Hughes Patrick M.
Kent John S.
Olejnik Orest
Allergan Sales Inc.
Hackler Walter A.
Page Thurman K.
Seidleck Brian K.
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