Quinuclidine derivatives

Details Quinuclidine derivatives Quinuclidine derivatives

Filed on

1995-03-14

Date issued

1997-12-16

Examiner

Rotman, Alan L.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Having -c-, wherein x is chalcogen, bonded directly to...

Other Related Categories

514292, 546 79, 546 81, 546 89, A61K 3144, C07D49108, C07D49508, C07D48708

Type

Patent

Status

active

Patent number

056985681

Description

ABSTRACT:
Quinuclidine derivatives of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein m, P, Z, Y, R.sup.1, R.sup.2 and R.sup.3 are as defined below. The compounds are substance P antagonists and, therefore, are useful in treating gastrointestinal disorders, central nervous system disorders, inflammatory diseases, pain and migraine.

REFERENCES:
patent: 2455949 (1947-06-01), Rieveschl, Jr. et al.
patent: 4097528 (1978-06-01), Porta et al.
patent: 4246201 (1981-01-01), Borzatta
patent: 5422354 (1995-06-01), Lowe, III

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