Antibacterial 7.beta.-heterocyclic-cephem

Details Antibacterial 7.beta.-heterocyclic-cephem Antibacterial 7.beta.-heterocyclic-cephem

1984-12-07

1987-09-22

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540227, C07D50118, A61K 31545

Patent

active

046955658

ABSTRACT:
This application discloses antibacterial cephems of the formula: ##STR1## wherein R.sub.1 represents hydrogen, alkyl, alkenyl, heterocyclylalkyl, or aralkyl; R.sub.3 is a 5- or 6-membered heterocyclic ring selected from: ##STR2## and X is sulfur or oxygen. Included also are pharmaceutically acceptable salts and esters of such compounds; pharmaceutical compositions thereof, and methods of treatment comprising such compositions when an antibiotic effect is needed.

REFERENCES:
patent: 4255424 (1981-03-01), Hannah
patent: 4283397 (1981-08-01), Hannah
patent: 4327210 (1982-04-01), Montavon et al.
patent: 4348518 (1982-09-01), Montavon et al.
patent: 4358447 (1979-04-01), Hannah
patent: 4412070 (1983-10-01), Reiner et al.
patent: 4474779 (1984-10-01), Nagano et al.
Nagano et al., "Cephalosporin Compounds", Chem. Abst. 98:89072u (1983).
Dunn, G. L., "Ceftizoxime and Other Third-generation Cephalosporins", J. Antimicrob. Chem. (1982) 10 Supp. C, 1-10.
John Hannah, et al.--"Quaternary Heterocyclylamino .beta.-Lactams: A Generic Alternative to the Classical Acylamino Side Chain", J. Med. Chem. 1982, 25, 457-469.

Affiliated with

Also associated with

Rating

Antibacterial 7.beta.-heterocyclic-cephem does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibacterial 7.beta.-heterocyclic-cephem, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibacterial 7.beta.-heterocyclic-cephem will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2058820