Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1995-10-31
1998-04-21
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4241841, 4242341, 4242471, 426 32, 426 42, 426 43, A61K 3907, A61K 3900, A61K 3902, A61K 3908
Patent
active
057414947
DESCRIPTION:
BRIEF SUMMARY
FIELD OF THE INVENTION
The present invention relates to a medicine or food which potentiates an immune function of a human being or an animal to thereby protect the human being or the animal from infection, or a feed having an immunopotentiative action.
BACKGROUND OF THE INVENTION
In recent years, a progress in immunology has allowed to think that various maladies and infectious diseases of a human being and an animal are caused by the lowering or incompleteness in the immune function.
Various antibiotics have so far been administered for with such maladies or infectious diseases such as bronchial asthma, allergies and the like. Meanwhile, overcrowded raising conditions in the fields of animal husbandry and aquaculture in order to efficiently raise livestock, poultry or fish, dosing of antibiotics in a large amount has been employed. Such practices often give rise to the incidence of antibiotic-resistant bacillus.
Various materials having an immunopotentiative action has so far been investigated. It is known that Bacillus subtilis Natto, Bacillus celleus, Bifidobacterium bifidum and Clostridium have a little immunopotentiative action. With respect to egg white, the immunopotentiative action thereof has been reported by the present inventors (Japanese patent publication-A 3-251537).
SUMMARY OF THE INVENTION
Described are compositions safe for humans and animals comprising Bacillus subtilis, egg white and optionally also garlic can synergistically increase the respective immunopotentiative actions.
That is, the present invention relates to an immunopotentiative and infection-protective agent comprising two or more members in combination selected from bacillus, egg white and garlic. The above bacillus is selected from the group consisting of Bacillus subtilis Natto, Bacillus celleus, Lactobacillus lactis, Lactobacillus casei, Bifidobacterium bifidum, and Clostridium.
The invention relates to the use of the above defined combination of two or more members for the pharmacological treatment and prevention of human beings and animals. Accordingly the invention relates to a pharmacological composition and a feed composition.
The invention provides a pharmacological method for treating or preventing a disease by administering a pharmacologically effective amount of the combination to human being or an animal by virtue of an immunopotentiative action, an infection protective action and/or an infection preventing action to provide by the combination of the invention.
Bacillus may, in the invention, include Bacillus substilis Natto, Streptococcus faecalis, Clostridium butyricum, Lactobacillus lactis and Bifidobacterium bifidum.
Bacillus may further includes Bacillaceae, Enterococcus and Lactobacillaceae. It may further includes Bacillus, Streptococcus, Clostridium and Lactobacillus.
Egg white includes natural egg white powder, egg white powder produced by fermenting with a bacillus or an enzyme to remove saccharides, sterilizing and drying and egg white powder produced by fermenting with a digesting enzyme.
The bacillus used in the present invention is selected from the bacilli described above. The condition of the bacillus is not specifically limited, and either raw bacillus or dead bacillus can be used. They are commercially available and can readily be obtained. A nutrient type is preferred.
The egg white used in the present invention is not specifically limited, and there can be used raw egg white, whole egg powder, or enzyme-treated egg white, and those containing a component constituting the egg white.
The processes of preparing the egg white will be shown below. treatment) with bacteria or fungus (e.g., yeast) and a sterilization treatment and then to drying and a pulverization treatment to prepare egg white powder. treatment) with bacteria or fungus (e.g., yeast) and a sterilization treatment. The egg white thus treated is subjected to removal of lysozyme with a conventional ion exchange resin deposition process or isoelectric crystallization process and then to drying to prepare egg white powder. treat
REFERENCES:
patent: 3885048 (1975-05-01), Liggett
patent: 4107334 (1978-08-01), Jolly
Derwent Abstract Accession No. 84-0020005 (Kimura 1974).
Derwent Abstract Accession No. 84-234713 (Tanaka 1984).
Araki Seiichi
Fujimoto Masatoshi
Suzuki Mamoru
Eisai Co. Ltd.
Housel James C.
Shaver Jennifer
LandOfFree
Immunopotentiative and infection-protective agent containing bac does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunopotentiative and infection-protective agent containing bac, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunopotentiative and infection-protective agent containing bac will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2055318