High affinity nucleic acid ligands of complement system proteins

Details High affinity nucleic acid ligands of complement system proteins High affinity nucleic acid ligands of complement system proteins

1998-02-12

2000-10-31

Zitomer, Stephanie

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 912, 536 231, 536 254, C07H 2104, C12Q 168, C12P 1934

Patent

active

06140490&

ABSTRACT:
Methods are described for the identification and preparation of high-affinity Nucleic Acid Ligands to Complement System Proteins. Methods are described for the identification and preparation of high affinity Nucleic Acid Ligands to Complement System Proteins C1q, C3 and C5. Included in the invention arc specific RNA ligands to C1q, C3 and C5 identified by the SELEX method.

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