Tissue moisturizing composition and method

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active...

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424 7802, A61K 922, A61K 952

Patent

active

059685000

ABSTRACT:
A composition and method of moisturizing mammalian membranous tissue is disclosed. The composition utilized in this method includes water, a bioadhesive polymer as the moisturizing agent, and preferably, a consistency-enhancing agent. The bioadhesive is a water-swellable, but water-insoluble, particulate, fibrous, cross-linked carboxy-functional polymer containing (a) a plurality of repeating units of which at least about 80 percent contain at least one carboxyl functionality, and (b) about 0.05 to about 1.5 percent cross-linking agent substantially free from polyalkenyl polyether. The consistency-enhancing agent, when present, is a water-soluble or -dispersible anionic or non-ionic polymer. The composition is contacted with the tissue to be moisturized, and that contact is maintained for a time period sufficient to moisturize the contacted area.

REFERENCES:
patent: 2923692 (1960-02-01), Ackerman
patent: 4032629 (1977-06-01), Osberghaus
patent: 4548990 (1985-10-01), Mueller
patent: 4552755 (1985-11-01), Rander
patent: 4615697 (1986-10-01), Robinson
patent: 4863725 (1989-09-01), Perkner et al.
patent: 4900554 (1990-02-01), Yanagabashi
Chem Ag. 99:110774g.
Chemical Abstracts, vol. 99, No. 14, Oct. 1983, p. 343, abstract 110774g citing to RO, A, 75553 (Intreprinderea De Antibiotice) Jan. 30, 1981.

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