Method of treating gram-negative bacterial infection by administ

Details Method of treating gram-negative bacterial infection by administ Method of treating gram-negative bacterial infection by administ

1996-06-03

2000-10-31

Degen, Nancy

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514152, 514192, 424114, 530319, 530350, 536136, 536 168, A61K 3817, C07G 1100, C07H 15234, C07K 1447

Patent

active

061403067

ABSTRACT:
The present invention relates to methods and compositions for treating gram-negative bacterial infections, using BPI protein products. Co-treatment, or concurrent administration, of BPI protein product with an antibiotic in treatment of gram-negative bacterial infections improves the therapeutic effectiveness of the antibiotic, including increasing antibiotic susceptibility of gram-negative bacteria and reversing resistance of the bacteria to antibiotics.

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