Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-06-26
2000-10-31
Myers, Carla J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 435 72, 435 724, 536 235, 536 2431, 536 2433, C12Q 168, C12P 1934, C07H 2104
Patent
active
061400505
ABSTRACT:
The invention relates to assays for determining breast cancer or melanoma. It has been found that the accuracy of such assays can be improved by assaying samples for three or more known tumor rejection antigen precursors. For breast cancer, the tumor rejection antigen precursors known as SCP-1, NY-ESO-1, and SSX-2 are assayed. For melanoma, SSX-2, NY-ESO-1, and MAGE-3 are assayed. Additional known tumor rejection antigen precursors can also be determined to confirm the assays. It is preferred to carry these out via polymerase chain reactions.
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Chen Yao-tseng
Old Lloyd J.
Pfreundschuh Michael
Sahin Ugur
Tureci Ozlem
Ludwig Institute for Cancer Research
Myers Carla J.
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