Process for the production of 2-substituted pyrido[4,3-b]-indole

Details Process for the production of 2-substituted pyrido[4,3-b]-indole Process for the production of 2-substituted pyrido[4,3-b]-indole

1980-01-15

1981-05-12

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D47104

Patent

active

042673313

ABSTRACT:
A process for production of certain 2-substituted-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole tranquilizing agents of the formula ##STR1## wherein X.sub.1 and Y.sub.1 are each hydrogen or fluoro; Z.sub.1 is hydrogen, fluoro or methoxy and n is 3 or 4 which comprises contacting an amine of the formula ##STR2## with an equimolar amount of a lactol of the formula ##STR3## wherein q is 1 or 2; in the presence of a reaction inert solvent under reductive alkylation conditions.

REFERENCES:
patent: 3382250 (1968-05-01), Johnson et al.
patent: 3687961 (1972-08-01), Bernstein et al.
patent: 3983239 (1976-09-01), Nagai et al.
patent: 3991199 (1976-11-01), Berger
patent: 4001263 (1977-01-01), Plattner et al.
patent: 4141980 (1979-02-01), Berger
Colonge et al., Bull. Soc. Chim. France, 1966, pp. 2005-2011.

Affiliated with

Also associated with

Rating

Process for the production of 2-substituted pyrido[4,3-b]-indole does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the production of 2-substituted pyrido[4,3-b]-indole, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of 2-substituted pyrido[4,3-b]-indole will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2047737