Use of 6.beta.-fluoro-7.alpha.-halogenocorticoids as topical ant

Details Use of 6.beta.-fluoro-7.alpha.-halogenocorticoids as topical ant Use of 6.beta.-fluoro-7.alpha.-halogenocorticoids as topical ant

1979-11-05

1981-05-12

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26023955D, 26039745, A61K 3158

Patent

active

042671736

ABSTRACT:
Described is the use of 6.beta.-fluoro-7.alpha.-halogeno-1,4-pregnadiene-17.alpha.,21-diol-3,20-di ones and their esters as topical anti-inflammatory agents, and pharmaceutical formulations thereof useful therefor. Preferred compounds are 6.beta.,9.alpha.-difluoro-7.alpha.-chloro (or bromo)-16.beta.-methyl-1,4-pregnadiene-11.beta.,17.alpha.,21-triol-3,20-di one 17-mono- and 17,21-di-lower alkanoates.

REFERENCES:
patent: 3148184 (1964-09-01), Gould et al.
patent: 3173914 (1965-03-01), Bowers
patent: 3264332 (1966-08-01), Gould et al.
patent: 3496273 (1970-02-01), Laurent et al.
patent: 3637668 (1972-01-01), Laurent et al.

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