Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-03-19
1998-12-22
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
536 231, 536 234, 536 235, 4352523, 4353201, 530350, C12P 2106, C07H 2102, C07H 2104, C07K 100
Patent
active
058517995
ABSTRACT:
The present invention provides a human histone-like protein (HLP) and polynucleotides which identify and encode HLP. In addition, the invention provides expression vectors and host cells, agonists, antibodies, and antagonists. The invention also provides methods for producing HTP and for treating disorders associated with the expression of HLP.
REFERENCES:
Kohnke-Godt, B. et al., "Heparin-Binding Lectin from Human Placenta: Further Characterization of Ligand Binding and Structural Properties and Its Relationship to Histones and Heparin-Binding Growth Factors", Biochemistry, 30: 55-65 (1991).
Rabbani, S.A. et al., "Nucleotide and (derived) amino acid sequence of a novel peptide from a rat (hypercalcemic) Leydig cell tumor", Biochim. Biophys. Acta, 1171: 229-230 (1992).
Rabbani, S.A. et al., (Direct Submission), GenBank Sequence Database (Accession 57064), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 57064).
Dobner, T. et al., "A novel divergently transcribed human histone H2A/H2B gene pair", DNA Sequence, 1: 409-413 (1991) (GI 1082448).
Rabbani et al. (1992) Biochim. Biophys. Acta 1171 : 229-230.
Bandman Olga
Goli Surya K.
Zhang Hong
Billings Lucy J.
Incyte Pharmaceuticals Inc.
Saidha Tekchand
Wax Robert A.
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