Photoemitting catheters and other structures suitable for use in

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Light application

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606 7, 606 15, A61N 501

Patent

active

058512250

ABSTRACT:
A structure generates electromagnetic radiation having at least one wavelength selected for activating a photo-sensitive substance that is applied to a tissue to be treated. The structure is particularly useful for photo-dynamic therapy (PDT) applications. The structure includes a body of material, such as a polymer filament, band, or substrate, that contains a gain medium. The gain medium in turn contains a substance (such as dye molecules) for generating a stimulated emission that includes the at least one wavelength when excited by a pump wavelength, and a plurality of scattering sites (such as scattering particles) for scattering the stimulated emission to provide a narrow band emission at the at least one selected wavelength. The narrow band emission in turn activates the photo-sensitive therapeutic substance.

REFERENCES:
patent: 4852567 (1989-08-01), Sinofsky
patent: 4957481 (1990-09-01), Gatenby
patent: 5434878 (1995-07-01), Lawandy
patent: 5448582 (1995-09-01), Lawandy
patent: 5625456 (1997-04-01), Lawandy
"Selective Absorption of UV Laser Energy by Human Atherosclerotic Plaque Treated with Tetracycline", D. Murphy-Chutorian, et al., American Journal of Cardiology, vol. 55, p. 1293, May 1985.
"Selective Absorption of Ultraviolet Laser Energy by Human Atherosclerotic Plaque Treated with Tetracycline", Douglas Murphy-Chutorian et al., American Journal of Cardiology, May 1, 1985, vol. 55, pp. 1293-1297.

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