Oligonucleotide N-alkylphosphoramidates

Details Oligonucleotide N-alkylphosphoramidates Oligonucleotide N-alkylphosphoramidates

1993-11-22

1996-05-21

Vogel, Nancy T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 241, 536 256, C07H 2102, C07H 2100, C07H 2104

Patent

active

055191266

ABSTRACT:
Oligonucleotide N-alkylphosphoramidates useful for combatting diseases by biochemical intervention at the RNA and DNA level are disclosed.

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patent: 4725677 (1988-02-01), Koster et al.
Thuong et al. (1985) Biochimie vol. 67: 673-684.
Uhlmann et al. (1990) Chemical Review vol. 90(4): 544-579.

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