Degradable monofilament and preparation process thereof

Details Degradable monofilament and preparation process thereof Degradable monofilament and preparation process thereof

1997-12-03

2000-07-18

Yoon, Tae

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

From carboxylic acid or derivative thereof

528370, 525415, 523105, 606230, 2642905, C08G 6308, C08G 6388, D02J 122, A61L 1700

Patent

active

060909102

ABSTRACT:
A degradable copolymer filament comprising an internal structure having the following separate phases: (a) a matrix phase comprised as a primary component of a polymer segment which exhibits a tensile Young's modulus of 2 GPa or less and a strength retention of 50% or more after two weeks in water at 37.degree. C., pH 7.3, and (b) a micro-dispersed phase comprised as a primary component of a polymer segment which exhibits a tensile strength of 200 MPa or more and a strength reduction greater than the matrix phase in water at 37.degree. C., pH 7.3. The weight ratio of each component in the matrix phase and dispersed phase is 50:50 to 95:5, respectively, and the dispersed phase a needle structure oriented by stretching in the fiber direction. A degradable monofilament having an excellent mechanical strength and flexibility, moderate hydrolyzability, high ligature stability and being suitable as a material of surgical absorbable suture can be obtained. A preparation process is also provided.

REFERENCES:
patent: 4700704 (1987-10-01), Jamiolkowski et al.
patent: 5252701 (1993-10-01), Jarrett et al.
patent: 5747637 (1998-05-01), Shinoda et al.
Bezwada et al, "Monocryl Suture, a New Ultra-Pliable Absorbable Monofilament Suture", Biomaterials, 16, (1995), pp. 1141-1148.

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