Benzothiophenes compounds which have useful pharmaceutical activ

Details Benzothiophenes compounds which have useful pharmaceutical activ Benzothiophenes compounds which have useful pharmaceutical activ

1998-08-04

2000-07-18

Davis, Zinna Northington

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514444, 514445, 514448, 549 52, 549 57, 549 58, C07D33352, A61K 3138

Patent

active

060908432

ABSTRACT:
This invention provides novel benzothiophene compounds of the formula I: ##STR1## which are useful for the treatment of the various medical conditions associated with postmenopausal syndrome, as well as estrogen dependent diseases including cancer of the breast, uterus, and cervix. The present invention further relates to pharmaceutical formulations of compounds of formula I.

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Kaufmann, et al., "Hypochloesterolemic Activity of . . . " J. Pharmacol. Exp. Ther., vol. 280, No. 1, Jan. 1997, pp. 146-153.

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