N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor sub

Details N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor sub N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor sub

1996-03-21

1997-12-30

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544294, 544360, 544376, 544380, 544146, 544107, 544175, 544194, 544202, 544203, 544204, 544196, 544257, 5442811, 5442841, 544285, 544180, C07D40110, C07D29515, C07D21114, C07D21170

Patent

active

057032351

ABSTRACT:
Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C.sub.1 -C.sub.6 alkoxy, --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1 or 2; or

REFERENCES:
patent: 5395835 (1995-03-01), Glase et al.
Murray et al., (1995), "A Novel Series of Arylpiperazines with High Affinity and Selectivity for the Dopamine D.sub.3 Receptor," Bioorg, Med. Chem. Let., vol. 5, No. 3, pp. 219-222.

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