Nonaqueous fluorinated drug delivery vehicle suspensions

Details Nonaqueous fluorinated drug delivery vehicle suspensions Nonaqueous fluorinated drug delivery vehicle suspensions

1994-06-14

1996-05-21

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424426, 424428, 424423, 424434, 424435, 424449, 424501, 514912, 514963, A61K 914, A61K 4734, A61K 4706, A61K 4732

Patent

active

055187315

ABSTRACT:
Nonaqueous pharmaceutical compositions for use in aqueous physiological systems are disclosed comprising drug delivery vehicles suspended in nonaqueous perfluorocarbon or fluorinated silicone liquid carriers. The suspended drug delivery vehicles may be water labile or water stable and incorporate therapeutic or diagnostic compounds which remain stable and pharmaceutically effective for extended periods. The pharmaceutical compositions have improved bioavailability, are capable of low dose volume delivery, and do not leach the incorporated therapeutic or diagnostic compounds into the liquid carriers making them well suited for multi-dose packaging and administration.

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International Search Report, Jul. 2, 1993.

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