Process for making antimicrobial compounds

Details Process for making antimicrobial compounds Process for making antimicrobial compounds

1996-11-14

1997-12-30

Datlow, Philip I.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540205, 540214, 540224, 540300, 540301, 540302, 540305, 540310, 540347, 540348, 544 586, 544101, 544235, 544236, 544256, 544279, 544362, 544363, 546 79, 546 80, 546 83, 546 90, 546101, 546123, 546156, C07D21556, C07D23728, C07D47104, C07D48704

Patent

active

057032319

ABSTRACT:
The present invention provides a process for making a compound having a structure according to Formula (I) ##STR1## wherein A.sup.1, A.sup.2 and A.sup.3 are independently carbon or nitrogen and R.sup.1, R.sup.3, R.sup.4 and R.sup.6 are known quinolone substituents; and wherein one of R.sup.1, R.sup.3 or R.sup.6 may be a lactam-containing moiety;

REFERENCES:
patent: 4379923 (1983-04-01), Bruynes et al.
patent: 4383946 (1983-05-01), Christensen et al.
patent: 4546176 (1985-10-01), Machida et al.
patent: 4684648 (1987-08-01), Tone et al.
patent: 4755513 (1988-07-01), Tone et al.
patent: 4833270 (1989-05-01), Bitha et al.
patent: 4841042 (1989-06-01), Habich et al.
patent: 4868295 (1989-09-01), Jaenicke et al.
patent: 4886810 (1989-12-01), Matsumoto et al.
patent: 5221741 (1993-06-01), Cecchetti et al.
patent: 5281703 (1994-01-01), White et al.
Chemical Abstract 99:139962c, Mitsui Petrochemical Ind. Ltd for JP 58-85,887 (May 23, 1983).
Chem. Abstract 114:82118d, Palamo-Nicolau et al. for EP 376,870 (Jul. 4, 1990).
Chu, D. T. W., I. M. Lico, A. K. Claiborne and H. Faubl, "An Alternative Synthesis of Temafloxacin, a Potent Antibacterial Agent", Can. J. Chem., vol. 70, No. 5, pp. 1323-1327 (May 1992).
Cecchetti, V. A. Fravolini and F. Schiafella, "One-Pot Synthesis of Rufloxacin", Synth. Commun., vol. 21, No. 22, pp. 2301-2308 (Dec. 1991).
Egawa, H. T. Miyamoto and J. Matsumoto, "A New Synthesis of Agent, Ofloxacin", Chem. Pharm. Bull., vol. 34, No. 10, pp. 4098-4102 (Oct. 1986).
Remuzon, P., D. Bouzard, P. Di Cesare, M. Essiz, J. P. Jacquet, J. R. Kiechel, B. Ledoussal, R. E. Kessler and J. Fung-Tomc, "Fluoronaphthyridines and Quinolones as Antibacterial Agents". 3. Synthesis and Structure-Activity Relationships of New 1-(I,I-Dimethyl-2-fluoroethyl), Chem., vol. 34, No. 1, pp. 29-37 (Jan. 1991).

Affiliated with

Also associated with

Rating

Process for making antimicrobial compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for making antimicrobial compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for making antimicrobial compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-203605