Method for inhibiting the dissolution of antiperspirant compound

Drug – bio-affecting and body treating compositions – Anti-perspirants or perspiration deodorants

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424 66, 424 67, 424 68, 424 47, A61K 732, A61K 734, A61K 736, A61K 738

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active

055187145

ABSTRACT:
A method of inhibiting the dissolution in anhydrous ethanol or isopropanol of a powdered aluminium-containing basic halide antiperspirant agent which comprises incorporating in the ethanol or isopropanol an amount effective to inhibit said dissolution of an alcohol soluble or alcohol-insoluble dissolution-inhibiting compound selected from the group consisting of compounds having a basic nitrogen function and compounds having a basic oxygen function. Examples of dissolution-inhibiting compounds are urea, thiorea, amino acids, C.sub.1 -C.sub.20 alkylamines and hydroxyalklyamines, inorganic bases, and alkali metal and alkaline-earth metal salts of inorganic acids and C.sub.1 -C.sub.20 organic carboxylic acids. The dissolution-inhibiting compound may alternatively be a particulate alcohol-insoluble inorganic drying agent such as a molecular sieve.

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