Chemistry: molecular biology and microbiology – Vector – per se
Patent
1996-10-07
2000-07-18
McKelvey, Terry
Chemistry: molecular biology and microbiology
Vector, per se
536 231, 536 235, 536 241, C12N 1563, C12N 1511, C12N 1512
Patent
active
060906189
ABSTRACT:
Disclosed is a smooth muscle cell specific promoter, the SM22.alpha. gene promoter as well as the murine cDNA and genomic SM22.alpha. nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22.alpha. promoter.
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Parmacek Michael S.
Solway Julian
ARCH Development Corporation
McKelvey Terry
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