Process for producing antibiotic A80190

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound

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435253, 435825, C12P 1300, C12N 120, C12R 103

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active

046832041

ABSTRACT:
Improved fermentation process for producing the polyether antibiotic A80190 which comprises cultivating a new strain of Actinomodura Oligospora, NRRL 15878, and the biologically purified culture of this microorganism are provided.

REFERENCES:
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patent: 4293650 (1981-12-01), Florent et al.
patent: 4407946 (1983-10-01), Labeda et al.
J. Tone et al., "CP-47, 433 and CP-47, 434, New Polycyclic Ether Antibiotics Produced by a New Species of Actinomadura, in "Current Chemotherapy and Infectious Disease", J. D. Nelson and C. Grassi, Eds., vol. I, American Society for Microbiology, Washington, D.C. 1980, pp. 469-470.
Nakamura et al., "A New species of Actinomadura Producing a Polyether Antibiotic, Cationomycin", J. Antibiotics 36, 1468-1472 (1983).
Derwent Abstract No. 83-834403/49 of European Patent 95-154-A to Fujisawa Pharm. KK.
"Polyether Antibiotics, Naturally Occurring Acid Ionophores, vol. 1, Biology", J. W. Westley, Ed., Marcel Dekker Inc., New York, 1982, pp. viii-xi.
"Polyether Antibiotics: Naturally Occurring Acid Ionophores, vol. 2, Chemistry, J. W. Westley Ed., Marcel Dekker, Inc., New York, 1983, p. 197 and excerpts from pp. 223-224.

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