Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-12-08
1991-04-09
Dentz, Bernard I.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546114, A61K 31435, C07D49504
Patent
active
050065327
ABSTRACT:
3-Hydroxyazabenzo[b]thiophene derivatives having optionally 2-aryl, 2-aralkyl, 2-alkyl or 2-alkenyl substituents were prepared by, among other methods, ring closure of an appropriately substituted benzylthio-alkoxycarbonyl-pyridine. These compounds are found to be useful in the treatment of pain, fever, inflammation, arthritic conditions, asthma, allergic disorders, skin diseases such as psoriasis and atopic eczema, cardiovascular disorders, inflammatory diseases and other leukotriene mediated diseases.
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Baker Robert K.
Durette Philippe L.
Pessolano Arsenio A.
Rupprecht Kathleen M.
Dentz Bernard I.
Merck & Co. Inc., Inc.
Panzer Curtis C.
Pfeiffer Hesna J.
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