Phencyclidine compounds and assays for its determination

Details Phencyclidine compounds and assays for its determination Phencyclidine compounds and assays for its determination

1981-12-22

1984-05-01

Kight, III, John

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 260121, 260172, 435 7, 435188, 424 85, C12N 996, G01N 3354, A61K 4300

Patent

active

044460651

ABSTRACT:
Novel oxime derivatives of phencyclidine are provided as precursors for conjugating proteins, either antigenic for the preparation of antibodies or enzymatic for the preparation of enzyme conjugates, which antibodies and enzyme conjugates find use as reagents in immunoassays. The combination of antibodies and enzyme conjugates provide for sensitive, accurate, rapid assays for phencyclidine without interference from commonly administered drugs, such as dextromethorphan, demerol and chlorpromazine.

REFERENCES:
patent: 4196185 (1980-04-01), Focella et al.
patent: 4281065 (1981-07-01), Lin et al.

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