Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-05-29
1987-07-28
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540302, 540303, C07D48704, A61K 31415
Patent
active
RE0324655
ABSTRACT:
Described is a novel process for the preparation of penems and carbapenems useful as antibacterial agents which comprises the reaction of an appropriate 4-substituted-azetidine-2-one with an acid halide in the presence of a tertiary amine and an alkaline earth metal carbonate, followed by reaction of the thereby formed 1-imido-4-substituted-azetidine-2-one with a trialkyl phosphite.
Also described are novel penems useful as antibacterials which are prepared by the described process.
REFERENCES:
patent: 4283531 (1981-08-01), Ganguly et al.
patent: 4576939 (1986-03-01), Ross et al.
Afonso Adriano
Hon Frank
Magatti Anita W.
Miller Stephen I.
Rizzo Nicholas S.
Rosen Gerald S.
Schering Corporation
LandOfFree
AZA penem compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with AZA penem compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and AZA penem compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2027932