Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-07-31
1993-09-14
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142278, 5142378, 514256, 514318, 514327, 544 60, 544130, 544335, 546194, 546209, 546210, 546221, A61K 31445, C07D41308, C07D40108
Patent
active
052449106
ABSTRACT:
A renin inhibiting compound of the formula: ##STR1## wherein X is O NH or S and G is a mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof; with the proviso that the compound is not N-(3-(4-Morpholino)propyl)-5(S)-(2(S)-(1(S)-(4-(methoxymethoxy)piperidin-1 -yl)carbonyl-2- phenyl)ethoxyhexanamido)-6-cyclohexyl-4(S)-hydroxy-2(S)-isopropylhexanamid e.
REFERENCES:
patent: 4895834 (1990-01-01), Hudspeth et al.
patent: 4900745 (1990-02-01), Hanson et al.
patent: 5055466 (1991-10-01), Weller et al.
Hamer, J. "Drugs for Heart Disease" Chapman and Hall publisher, 1979.
Baker William R.
Boyd Steven A.
Denissen Jon F.
Fung Anthony K. L.
Hutchins Charles W.
Abbott Laboratories
Chang Celia
Crowley Steven R.
Ivy C. Warren
LandOfFree
Renin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Renin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Renin inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2026809