Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-05-03
1997-12-30
Davis, Zinna Northington
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514374, 514378, 5462714, 5462721, 548235, 548247, C07D41302, C07D26102, A61K 3144, A61K 3141
Patent
active
057030995
ABSTRACT:
We proposed a novel compound having an activity of PGI.sub.2 receptor agonist.
A phenoxyacetic acid derivative of the formula ##STR1## A is --C(R.sup.1).dbd.N.about.OR.sup.2, --CH(R)NH--OR.sup.2, --COE, --SO.sub.2 E, --CH.sub.2 --NR.sup.3 --Y, --Z--NR.sup.3 --CONR.sup.4 R.sup.5, --CH.sub.2 --OR.sup.6, --CO.sub.2 R.sup.6, --CH.sub.2 --O.about.N.dbd.CR.sup.7 R.sup.8, --CH.sub.2 --O--NHCHR.sup.7 R.sup.8, substituted by imidazolyl(methyl), pyrazolylmethyl, oxazolyl(methyl), thioxazolyl, isoxazolyl, isothiazolyl, oxadiazolyl, triazolylmethyl;
REFERENCES:
patent: 5254576 (1993-10-01), Romine et al.
Chemical Abstracts, vol. 62, No. 5, Abstract 5.546g, Mar. 1, 1965.
Hamanaka Nobuyuki
Takahashi Kanji
Tokumoto Hidekado
Davis Zinna Northington
Ono Pharmaceutical Co. Ltd.
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