Process for preparing optically active 3-phenylglycidic acid est

Details Process for preparing optically active 3-phenylglycidic acid est Process for preparing optically active 3-phenylglycidic acid est

1990-09-07

1993-09-14

Robinson, Allen J.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435123, 435824, 435832, 435840, 435843, 435850, 435859, 435863, 435874, 435878, 435910, 435921, 435938, 540491, C07D28102

Patent

active

052448037

ABSTRACT:
There is disclosed a process for preparing optically active 3-phenylglycidic acid ester compound, which comprises permitting a culture broth, cells or treated cells of a microorganism having an ability of stereoselectively hydrolyzing a (2R, 3S)-3-phenylglycidic acid ester compound to act on a racemic 3-phenylglycidic acid ester compound which may also have a substituent on the phenyl group, thereby hydrolyzing the (2R, 3S) optically active isomer and separating and collecting the (2S, 3R) antipode from the reaction mixture.

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