N-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine recepto

Details N-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine recepto N-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine recepto

1996-04-15

1997-12-30

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544328, 544331, 544360, 544363, 544376, 544380, A61K 31495

Patent

active

057030839

ABSTRACT:
Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addidon salts thereof wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 independently represent hydrogen, halogen, hydroxy, alkyl, alkoxy, amino, aminosulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl, cyano, nitro, trifluoromethyl, or trifluoromethoxy;

REFERENCES:
patent: 5250528 (1993-10-01), Oku et al.
patent: 5364849 (1994-11-01), Cliffe et al.
patent: 5395835 (1995-03-01), Glase et al.
Murray et al., (1995), "A Novel Series of Arylpiperazines with High Affinity and Selectivity for the Dopamine D.sub.3 Receptor," Bioorg. Med. Chem. Let., vol. 5, No. 3, pp. 219-222.

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