Leydig cell stimulator

Details Leydig cell stimulator Leydig cell stimulator

1991-06-18

1994-04-19

Witshyn, Michael G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 514 15, 530397, 530398, 530399, 530416, 530417, 935 60, A61K 3700, A61K 3738

Patent

active

053046030

ABSTRACT:
The present invention relates to a compound which when administered to Leydig cells in the testes stimulates the production of androgen such as testosterone. This compound, when mixed with other known compounds, can produce testosterone levels in excess of those obtained by the administration of a maximal stimulatory dose of Lutenizing Hormone (LH).

REFERENCES:
patent: 5166190 (1992-11-01), Mather et al.
"Molecular Cell Biology", J. Darnell, et al., pp. 221-222 and pp. 260-262.
"Protein Purificaiton Methods: A Practical Approach", E. L. V. Harris, S. Angal, eds., pp. 9-10, 57-64.
A. J. W. Hsueh, et al., Proc. Natl. Acad. Sci. USA 84, 5082-5086 (1987).

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