3-(3-Substituted aryloxy)-2-yridinecarbonitriles, pharmaceutical

Details 3-(3-Substituted aryloxy)-2-yridinecarbonitriles, pharmaceutical 3-(3-Substituted aryloxy)-2-yridinecarbonitriles, pharmaceutical

1979-09-27

1980-10-21

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546288, 546300, A61K 3144

Patent

active

042294576

ABSTRACT:
New 3-(3-methoxyphenoxy)-2-pyridinecarbonitriles, which are useful as pharmacological agents, especially as agents for the treatment of senility and reversal of amnesia, are disclosed. Other known 3-(3-substituted phenoxy)-2-pyridinecarbonitriles are disclosed having the same utility. The compounds can be produced by dehydrating the appropriately substituted oxime or displacing an alkoxy group to give the desired carbonitrile.

REFERENCES:
patent: 4187311 (1980-02-01), Butler
patent: 4187379 (1980-02-01), Butler
Villani et al., Journal of Medicinal Chemistry, vol. 18, No. 1, pp. 1-9, (1975).

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