Novel 2,2-dimethyl steroids

Details Novel 2,2-dimethyl steroids Novel 2,2-dimethyl steroids

1976-08-31

1978-03-07

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2603973, 26039747, C07J 500, A61K 3156

Patent

active

040780597

ABSTRACT:
Novel 2,2-dimethyl steroids of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, --OH and ##STR2## R.sub.1 is selected from the group consisting of hydrogen and hydrocarbon of 1 to 17 carbon atoms Z is selected from the group consisting of hydrogen and ##STR3## in the .alpha.-position, R.sub.2 is alkyl of 1 to 4 carbon atoms and the dotted line in the B ring indicates the optional presence of a double bond in the 6(7) position having antialdosterone activity and increasing sodium diuresis while conserving organic potassium.

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