Polypeptide hormones of the thymus

Details Polypeptide hormones of the thymus Polypeptide hormones of the thymus

1975-08-22

1978-03-07

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

040779491

ABSTRACT:
There are disclosed closely related new polypeptides isolated from bovine thymus, which are distinct polypeptides denoted as Thymin I and Thymin II or Thymopoietin I and Thymopoietin II, respectively. Thymin I may be characterized as having a relative mobility (Rf) on 7% polyacrylamide gel disc electrophoresis of 0.63 with respect to methyl green at a pH of 4.3, and having the following structural sequence:

REFERENCES:
Goldstein et al.: Annals N. Y. Acad. Sci., 183, 230-240 (1971).
Goldstein: Triangle, 11, 7-14 (1972).
Goldstein: The Lancet, 119-122 (July 20, 1968).

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