Process for the purifying of iopamidol

Details Process for the purifying of iopamidol Process for the purifying of iopamidol

1994-07-29

1996-11-05

Kumar, Shailendra

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564152, 424 9454, C07C23122

Patent

active

055719414

ABSTRACT:
A process for purifying Iopamidol which uses a butanol as solvent is described. Iopamidol is obtained with high yields, also starting from aqueous solutions of the same and has characteristics in accordance with those required by pharmacopoeia.

REFERENCES:
patent: 4001323 (1977-01-01), Felder et al.
patent: 4352788 (1982-10-01), Felder et al.
patent: 5066823 (1991-11-01), Felder et al.
patent: 5204086 (1993-04-01), Wille
"Analytical Profiles of Drug Substances", vol. 17, pp. 115-154, Academic Press, San Diego, 1988.
U.S. Pharmacopeia xxii, P. 712, 1990.
Boll. Chim. Farm., 120, 639 (1981).
Merck Index 10th Edition, 4915, p. 731, 1983.

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