PDGF receptor blocking peptides

Details PDGF receptor blocking peptides PDGF receptor blocking peptides

1991-05-06

1993-12-07

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 15, 514 17, 530324, 530325, 530329, 530350, C07K 706, C07K 708, C07K 710, A61K 3702

Patent

active

052683583

ABSTRACT:
Methods and compositions are provided for treating several acute disease states associated with smooth muscle cell proliferation as well as the chronic process of atherogenesis utilizing oligopeptides corresponding to regions of the PDGF receptor protein. The oligopeptides can be used to block PDGF binding and activation for numerous applications, and can serve as immunogens to raise receptor-specific antibodies.

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