Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1992-05-12
1993-12-07
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424422, 424423, 424428, 424433, A61F 200
Patent
active
052681785
ABSTRACT:
Methods are disclosed for preventing or treating infection in a living patient at the site of a void in the patient's body created by surgery. The methods involve the use of biodegradable antibiotic implants which are placed in the surgical void and then supply an extended, continuous supply of at least one antibiotic to the surrounding tissue. The biodegradable implant comprises at least one biodegradable material such as polylactic acid, and at least one antibiotic drug. These components are combined and formed into bead, rods, or a gel which can be placed in the surgical void. The implant preferably comprises a plurality of antibiotics, each of which is specific to a different bacteria, which bacteria may be expected to be present at the site of the surgical
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Calhoun Jason H.
Mader Jon T.
Page Thurman K.
Spear James M.
The Board of Regents The University of Texas System
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