Fully integrated miniaturized planar liquid sample handling and

Liquid purification or separation – With means to add treating material – Chromatography

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210656, 204451, 204601, 422 69, 422 70, B01D 1508

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active

055714102

ABSTRACT:
A miniaturized total analysis system (".mu.-TAS") comprising a miniaturized planar column device is described for use in liquid phase analysis. The .mu.-TAS comprises microstructures fabricated by laser ablation in a variety of novel support substrates. The .mu.-TAS includes associated laser-ablated features required for integrated sample analysis, such as analyte detection means and fluid communication means. .mu.-TAS constructed according to the invention is useful in any analysis system for detecting and analyzing small and/or macromolecular solutes in the liquid phase and may employ chromatographic separation means, electrophoretic separation means, electrochromatographic separation means, or combinations thereof.

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