Substituted N-benzylpiperidine amides

Details Substituted N-benzylpiperidine amides Substituted N-benzylpiperidine amides

1989-09-05

1992-03-24

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514318, 514320, 514326, 514329, 546193, 546194, 546196, 546202, 546205, 546207, 546212, 546213, 546214, 546224, 546237, A61K 31445, C07D40106, C07D40112

Patent

active

050989154

ABSTRACT:
Substituted N-benzylpiperidine amides, which have activity as Class III antiarrhythmic agents, acting by prolonging cardiac action potential repolarization. The invention further provides for compositions incorporating the compunds and methods of their use, as well as providing for pharmaceutically acceptable salts of the compounds.

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Fleming, J. S., "Effects . . . Antihypertensive Agent," Federation Proceedings, vol. 43, p. 553, 1984.

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