Inhibition of angiogenesis

Details Inhibition of angiogenesis Inhibition of angiogenesis

1989-05-17

1991-03-19

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514171, 514177, 514178, 514182, A61K 31725, A61K 3156

Patent

active

050011162

ABSTRACT:
Angiogenesis in mammals is inhibited by administration of the active agents (1) heparin or a heparin fragment which is a hexasaccharide or larger or analogous compounds and (2) a steroid having 17.alpha.- and 21-hydroxy groups, 3- and 20-one groups, and in the 16-position hydrogen hydroxy or a methyl group, and non-toxic physiologically acceptable carboxylates, acetals, ketals and phosphates thereof.

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