Organic diamine therapeutic compositions

Details Organic diamine therapeutic compositions Organic diamine therapeutic compositions

1982-03-01

1983-11-08

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546140, 546148, 546149, 546191, 546194, 546208, 546201, 546229, 546230, 546232, 546264, 546273, 546281, 546304, 546312, 548465, 548470, 548482, 548524, 548566, 564388, 424244, 424246, 42424856, 424258, 424263, 424274, 424304, 424330, 544 39, 544 60, 544 62, A61K 31445, C07D40110

Patent

active

044142200

ABSTRACT:
A series of organic diamine base compounds derived from either an aromatic, alicyclic or heterocyclic ring and possessing, for the most part, an intervening methylene group between the ring and the aforesaid basic moiety have been prepared, including their pharmaceutically acceptable acid addition salts as well as oral pharmaceutical compositions containing same. These particular compounds are found to be useful in therapy as oral hypoglycemic agents. Preferred member compounds include 1,1'-[1,2-phenylenebis(methylene)]bispiperidine, 2,3-dihydro-2-[2-(1-piperidinomethyl)phenylmethyl]-1H-isoindole and 2,3-dihydro-2-[2-(4-morpholinomethyl)phenylmethyl]-1H-isoindole. Alternate methods of preparation are provided and the two principal synthetic routes leading to these compounds are described in some detail.

REFERENCES:
Knollmueller "Monatshefte fur Chemie", vol. 105, No. 1, pp. 114-122 (1974).

Affiliated with

Also associated with

Rating

Organic diamine therapeutic compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Organic diamine therapeutic compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Organic diamine therapeutic compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2007588